Weekly Chest CasesArchive of Old Cases

Case No : 213 Date 2001-11-23

  • Courtesy of Hye Jin Kim, M.D., In Sun Lee, M.D., Jin Seong Lee, M.D., Koun-Sik Song, M.D. / Asan Medical Center, Seoul, Korea
  • Age/Sex 27 / M
  • Chief ComplaintKnown cerebral infarction. Incidentally detected abnormal chest radiograph
  • Figure 1
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  • Figure 4

Diagnosis With Brief Discussion

Diagnosis
Pulmonary Hemosiderosis associated with Mitral Stenosis
Radiologic Findings
Chest radiograph shows numerous tiny nodules in both lungs. Pulmonary vascular cephalization, double contour overlying the right atrial shadow and effacement of the cardiac waist with normal cardiac size are noted. HRCT scan shows multiple nodules randomly distributed in both lungs. These are suggested pulmonary hemosiderosis possibly due to long-standing mitral stenosis. On echocardiography, severe mitral stenosis was noted with thrombi in enlarged left atrium. Cerebral infarction was thought to be due to emboli from LA thrombus. The patient was diagnosed as having mitral stenosis several years ago.
Brief Review
Typical radiographic findings in mitral stenosis include pulmonary vascular cephalization; interstitial, perivascular, and occasionally alveolar pulmonary edema; diffuse alveolar hemorrhage; hemosiderosis; and pulmonary ossification. Pulmonary hemosiderosis (deposition of blood pigments in the interstitial tissues) secondary to mitral disease is a frequent pathologic finding, but is not commonly recognized as such on chest films. If sufficient amounts of these deposits are present, they are visible roentgenographically as fine granular or miliary shadows throughout the lungs. They may become large enough to produce nodular densities ranging from 2 to 5 mm in diameter. The appearance of the lungs may resemble that noted in miliary tuberculosis or early nodular silicosis. Small, ill-defined nodules or coarse reticular opacity can be seen.
References
1. Kevin Woolley, Paul Stark. Pulmonary parenchymal manifestations of mitral valve disease. Radiographics 1999; 19:965-972.
2. John H. Juhl, Andrew B. Crummy, Janet E. Kuhlman. Paul and Juhl`s essentials of radiologic imaging. 7th ed. Linppincott-Raven, Philadelphia, 1998;1231-1234
Keywords
Lung, Metabolic and storage lung disesae,

No. of Applicants : 16

▶ Correct Answer : 3/16,  18.8%
  • - 源€愿€
  • - CHU Nancy-Brabois, France Denis Regent
  • - MH{CTC} GOLIBAR MAIDAN, India Vivek Sharma
▶ Semi-Correct Answer : 1/16,  6.3%
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